AB Variant Gangliosidosis GM2

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AB Variant Gangliosidosis GM2

AB Variant Gangliosidosis GM2

Inherited diseases characterized by the accumulation of G(M2) GANGLIOSIDE in central nervous system lysosomes and variably in other tissues. Subtypes include TAY-SACHS DISEASE and SANDHOFF DISEASE, as well as an AB variant of BETA-N-ACETYLHEXOSAMINIDASE deficiency and an adult onset form of GM2 Gangliosidosis.

RELATED TERMS
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Diseases
A definite pathologic process with a characteristic set of signs and symptoms. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown.

Central
In anatomy and medicine (as elsewhere), central is the opposite of "peripheral" which means away from the center.

DISEASE
Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the rubella (German measles) virus.

Adult
A person having attained full growth or maturity. Adults are of 19 through 44 years of age.

Gangliosidosis
A group of often fatal inherited diseases marked by the accumulation of GANGLIOSIDES in LYSOSOMES secondary to enzymatic deficiency states. Gangliosidoses include TAY- SACHS DISEASE; GANGLIOSIDOSIS GM1; GANGLIOSIDOSES GM2; and SANDHOFF DISEASE; which share the infantile or childhood onset of CENTRAL NERVOUS SYSTEM deterioration. (Menkes, Textbook of Child Neurology, 5th ed, pp89-97)

SIMILAR TERMS
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PREVIOUS AND NEXT TERMS
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Abandonment, Patient
Refusal of the health professional to initiate or continue treatment of a patient or group of patients. The refusal can be based on any reason. The concept is differentiated from PATIENT REFUSAL OF TREATMENT see TREATMENT REFUSAL which originates with the patient and not the health professional.

Abandoned Child
A child who is deserted by parents or parent substitutes without regard for its future care.

Abactrim
This drug combination has proved to be an effective therapeutic agent with broad-spectrum antibacterial activity against both gram-positive and gram-negative organisms. It is effective in the treatment of many infections, including Pneumocystis carinii pneumonia in AIDS, but is the drug of choice for urinary infection.

Abactal
A synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria.

ABaC50,005
A partial adrenergic agonist with functional beta 1-receptor specificity and inotropic effect. It is effective in the treatment of acute cardiac failure, postmyocardial infarction low-output syndrome, shock, and reducing orthostatic hypotension in the Shy-Drager syndrome.

AB Variant Gangliosidosis GM2

Aarane
A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.

Abdominal Aortic Aneurysm
An aneurysm in that part of the aorta continuing from the thoracic region and giving rise to the inferior phrenic, lumbar, median sacral, mesenteric, renal, and ovarian or testicular arteries.

Abdominal Aortas
The aorta from the diaphragm to the bifurcation into the right and left common iliac arteries.

Abdominal Abscesses
An abscess located in the abdominal cavity, i.e., the cavity between the diaphragm above and the pelvis below. (From Dorland, 27th ed)

Abdomens, Acute
Clinical syndrome characterized by abdominal pain of great severity associated with other symptoms and signs, usually those of acute peritonitis, which might well be the result of a ruptured abdominal viscus or a similar abdominal catastrophe requiring urgent surgical operation.

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gang,iosidosis gm2 / ab variant gangkiosidosis gm2 / ab variant gangiiosidosis gm2 / ab variant ganglosidosis gm2 / ab variant gangli9sidosis gm2 / ab variant gangli0sidosis gm2 / ab variant ganglipsidosis gm2 / ab variant ganglilsidosis gm2 / ab variant gangliksidosis gm2 / ab variant gangliisidosis gm2 / ab variant gangli8sidosis gm2 / ab variant gangliowidosis gm2 / ab variant ganglioeidosis gm2 / ab variant gangliodidosis gm2 / ab variant ganglioxidosis gm2 / ab variant gangliozidosis gm2 / ab variant ganglioaidosis gm2 / ab variant ganglioqidosis gm2 / ab variant gangliosdosis gm2 / ab variant gangliosieosis gm2 / ab variant gangliosirosis gm2 / ab variant gangliosifosis gm2 / ab variant gangliosivosis gm2 / ab variant gangliosicosis gm2 / ab variant gangliosixosis gm2 / ab variant gangliosisosis gm2 / ab variant gangliosiwosis gm2 / ab variant gangliosid9sis gm2 / ab variant gangliosid0sis gm2 / ab variant gangliosidpsis gm2 / ab variant gangliosidlsis gm2 / ab variant gangliosidksis gm2 / ab variant gangliosidisis gm2 / ab variant gangliosid8sis gm2 / ab variant gangliosidowis gm2 / ab variant gangliosidoeis gm2 / ab variant gangliosidodis gm2 / ab variant gangliosidoxis gm2 / ab variant gangliosidozis gm2 / ab variant gangliosidoais gm2 / ab variant gangliosidoqis gm2 / ab variant gangliosidoss gm2 / ab variant gangliosidosiw gm2 / ab variant gangliosidosie gm2 / ab variant gangliosidosid gm2 / ab variant gangliosidosix gm2 / ab variant gangliosidosiz gm2 / ab variant gangliosidosia gm2 / ab variant gangliosidosiq gm2 / ab variant gangliosidosis tm2 / ab variant gangliosidosis gn2 / ab variant gangliosidosis gj2 / ab variant gangliosidosis gk2 / ab variant gangliosidosis g,2 / ab variant gangliosidosis g 2 / ab variant gangliosidosis gm3 / ab variant gangliosidosis gme / ab variant gangliosidosis gmw / ab variant gangliosidosis gmq / ab variant gangliosidosis gm1 /